ISPAN LAVANDASI (LAVANDULA STOECHAS L.) XOMASHYOSINING FARMAKOGNOSTIK O'RGANISH VA STANDARTLASH PARAMETRLARINI BELGILASH.
Keywords:
Lavandula stoechas L.; farmakognoziya; efir moyi; GS/MS tahlili; flavonoidlar; standartlash; antimikrob faollik; antioxidant.Abstract
Ispan lavandasi (Lavandula stoechas L.) xom ashyosini farmakognostik jihatdan kompleks o'rganish va xalqaro farmakopeyalar talablariga mos keluvchi standartlash mezonlarini ishlab chiqish. Namunalar 2024-2025 yillarda Andijon viloyatidan yig'ildi. GS/MS tahlili, YUSSX (HPLC), yuqori unumli qatlam xromatografiyasi (YUQX/TLC), spektrofotometriya va anatomik-morfologik usullar qo'llanildi. Barcha tajribalar uch marta takrorlangan (n=6). L. stoechas efir moyi miqdori 2,1±0,2 mL/100g ni tashkil etdi. Asosiy komponentlar: kamfora (32,4±2,1%), fenshon (28,6±1,8%), 1,8-sineol (14,2±1,3%). Jami flavonoidlar miqdori 3,24±0,18 g/100g (kversetin ekvivalentida). Efir moyining antimikrob faolligi S. aureus ga nisbatan MIC 0,31 mg/mL, antioxidant faolligi (DPPH) IC₅₀ 0,35±0,02 mg/mL ni tashkil etdi. Standartlash ko'rsatkichlari: namlik 9,2±0,4%, umumiy kul 7,8±0,3%.
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