AGE-RELATED REMODELING OF THE THYMUS IN INFANTS WITH NECROTIZING ENTEROCOLITIS
Abstract
Necrotizing enterocolitis (NEC) is a severe inflammatory and necrotizing intestinal disease of infancy, especially common in premature and low-birth-weight newborns. Although intestinal injury is the principal manifestation, the disease may also involve central and peripheral immune organs. The thymus is particularly important because it plays a key role in the maturation and differentiation of T lymphocytes. In the dissertation, thymic changes were studied separately in the early neonatal period, late neonatal period, and later infancy.
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